Pyridines and derivatives
Aromatic organic compounds consist of an aromatic six-membered ring containing one nitrogen atom and five carbon atoms; includes compounds derived from pyridines.
Quantity
- (4)
- (1)
- (5)
- (5)
- (520)
- (22)
- (2,105)
- (22)
- (2)
- (5)
- (5)
- (271)
- (175)
- (1)
- (14)
- (50)
- (300)
- (86)
- (225)
- (6)
- (4)
- (2)
- (2)
- (3)
- (1)
- (1)
- (1)
- (1)
- (5)
- (1)
- (12)
- (4)
- (8)
- (7)
- (12)
- (60)
- (867)
- (5)
- (55)
- (60)
- (58)
- (19)
- (346)
- (2)
- (4)
- (2)
- (1)
- (1)
- (5)
- (275)
- (1)
- (1,700)
- (2)
- (27)
- (7)
- (1)
- (92)
- (4)
- (13)
- (77)
- (128)
- (54)
- (59)
- (2)
- (1)
- (1)
- (2)
- (1)
- (1)
Molecular Weight (g/mol)
- (1)
- (1)
- (1)
- (2)
- (5)
- (2)
- (1)
- (1)
- (2)
- (1)
- (2)
- (2)
- (3)
- (1)
- (1)
- (1)
- (2)
- (1)
- (2)
- (9)
- (4)
- (1)
- (2)
- (4)
- (2)
- (1)
- (5)
- (17)
- (23)
- (1)
- (1)
- (60)
- (21)
- (1)
- (1)
- (29)
- (49)
- (7)
- (2)
- (1)
- (5)
- (6)
- (12)
- (1)
- (1)
- (1)
- (18)
- (1)
- (14)
- (4)
- (1)
- (11)
- (5)
- (1)
- (10)
- (15)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (9)
- (7)
- (1)
- (2)
- (1)
- (4)
- (6)
- (2)
- (1)
- (1)
- (1)
- (4)
- (4)
- (1)
- (1)
- (5)
- (15)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (12)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (2)
- (2)
- (1)
- (15)
- (17)
- (4)
- (2)
- (2)
- (5)
- (2)
- (3)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (7)
- (5)
- (9)
- (1)
- (2)
- (1)
- (1)
- (1)
- (2)
- (1)
- (16)
- (7)
- (5)
- (1)
- (1)
- (3)
- (5)
- (10)
- (2)
- (1)
- (6)
- (6)
- (7)
- (12)
- (1)
- (1)
- (39)
- (1)
- (12)
- (11)
- (4)
- (2)
- (2)
- (15)
- (15)
- (1)
- (1)
- (1)
- (2)
- (9)
- (3)
- (2)
- (1)
- (1)
- (3)
- (6)
- (3)
- (3)
- (1)
- (3)
- (1)
- (1)
- (1)
- (3)
- (3)
- (1)
- (6)
- (5)
- (2)
- (1)
- (19)
- (9)
- (1)
- (2)
- (1)
- (1)
- (1)
- (22)
- (22)
- (2)
- (2)
- (1)
- (1)
- (2)
- (2)
- (22)
- (16)
- (6)
- (2)
- (1)
- (1)
- (2)
- (7)
- (2)
- (3)
- (1)
- (1)
- (2)
- (1)
- (8)
- (17)
- (2)
- (1)
- (6)
- (1)
- (3)
- (1)
- (2)
- (1)
- (6)
- (2)
- (4)
- (2)
- (1)
- (1)
- (1)
- (6)
- (2)
- (3)
- (3)
- (3)
- (5)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (6)
- (1)
- (1)
- (2)
- (5)
- (3)
- (1)
- (4)
- (12)
- (48)
- (1)
- (4)
- (2)
- (3)
- (1)
- (2)
- (1)
- (1)
- (7)
- (9)
- (22)
- (30)
- (1)
- (1)
- (3)
- (2)
- (2)
- (4)
- (11)
- (5)
- (1)
- (1)
- (55)
- (6)
- (1)
- (7)
- (2)
- (1)
- (1)
- (1)
- (2)
- (2)
- (4)
- (1)
- (1)
- (1)
- (1)
- (2)
- (6)
- (4)
- (15)
- (5)
- (2)
- (1)
- (1)
- (1)
- (1)
- (3)
- (10)
- (1)
- (17)
- (9)
- (1)
- (1)
- (2)
- (4)
- (4)
- (1)
- (1)
- (1)
- (1)
- (2)
- (3)
- (11)
- (13)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (10)
- (23)
- (1)
- (16)
- (2)
- (2)
- (1)
- (1)
- (2)
- (6)
- (3)
- (1)
- (1)
- (7)
- (11)
- (3)
- (2)
- (1)
- (1)
- (2)
- (4)
- (5)
- (1)
- (1)
- (1)
- (2)
- (2)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (34)
- (3)
- (4)
- (4)
- (3)
- (1)
- (2)
- (1)
- (1)
- (2)
- (2)
- (5)
- (3)
- (5)
- (8)
- (4)
- (2)
- (1)
- (1)
- (1)
- (2)
- (2)
- (1)
- (2)
- (4)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (10)
- (2)
- (17)
- (1)
- (13)
- (2)
- (3)
- (1)
- (5)
- (18)
- (1)
- (13)
- (1)
- (1)
- (1)
- (1)
- (3)
- (1)
- (18)
- (11)
- (18)
- (1)
- (1)
- (3)
- (1)
- (17)
- (8)
- (6)
- (2)
- (2)
- (2)
- (2)
- (1)
- (4)
- (4)
- (1)
- (3)
- (2)
- (7)
- (11)
- (2)
- (2)
- (2)
- (4)
- (1)
- (8)
- (5)
- (6)
- (24)
- (2)
- (1)
- (2)
- (6)
- (1)
- (4)
- (1)
- (1)
- (2)
- (2)
- (1)
- (2)
- (9)
- (12)
- (1)
- (12)
- (26)
- (8)
- (1)
- (1)
- (1)
- (7)
- (9)
- (1)
- (1)
- (1)
- (3)
- (1)
- (15)
- (5)
- (2)
- (2)
- (3)
- (4)
- (2)
- (1)
- (5)
- (3)
- (1)
- (2)
- (1)
- (2)
- (3)
- (1)
- (1)
- (1)
- (1)
- (8)
- (6)
- (1)
- (2)
- (2)
- (7)
- (1)
- (1)
- (11)
- (8)
- (1)
- (3)
- (4)
- (1)
- (2)
- (6)
- (6)
- (2)
Percent Purity
- (1)
- (1)
- (1)
- (2)
- (3)
- (2)
- (1)
- (2)
- (1)
- (1)
- (3)
- (2)
- (1)
- (2)
- (2)
- (1)
- (3)
- (6)
- (1)
- (5)
- (27)
- (2)
- (15)
- (4)
- (3)
- (9)
- (4)
- (4)
- (18)
- (8)
- (2)
- (4)
- (7)
- (1)
- (32)
- (2)
- (75)
- (1)
- (4)
- (53)
- (1)
- (3)
- (1)
- (10)
- (6)
- (33)
- (6)
- (1)
- (1)
- (106)
- (1)
- (9)
- (544)
- (5)
- (462)
- (42)
- (22)
- (130)
- (9)
- (1)
- (117)
- (1)
- (2)
- (3)
- (1)
- (1)
- (27)
- (32)
- (15)
- (4)
- (13)
- (12)
- (1)
- (2)
- (2)
- (13)
- (1)
- (2)
- (2)
- (1)
- (2)
- (20)
- (1)
- (1)
- (1)
- (1)
- (27)
- (6)
- (1)
- (1)
- (4)
- (5)
- (4)
- (5)
- (3)
- (1)
- (3)
- (1)
- (47)
- (1)
- (11)
- (364)
- (5)
- (3)
- (133)
- (1,015)
- (4)
- (2)
- (1)
- (3)
- (12)
- (904)
- (7)
- (35)
- (7)
- (2)
- (1)
- (418)
- (26)
- (4)
- (10)
- (1)
- (1)
- (4)
- (1)
- (2)
- (6)
- (2)
- (4)
- (1)
- (4)
Physical Form
- (1)
- (3)
- (19)
- (2)
- (8)
- (72)
- (4)
- (1,561)
- (2)
- (4)
- (12)
- (9)
- (1)
- (14)
- (3)
- (9)
- (3)
- (2)
- (5)
- (4)
- (2)
- (1)
- (16)
- (3)
- (13)
- (11)
- (13)
- (10)
- (2)
- (2)
- (1)
- (2)
- (2)
- (408)
- (5)
- (6)
- (2)
- (7)
- (2)
- (3)
- (2)
- (237)
- (3)
- (2)
- (3)
- (18)
- (5)
- (2)
- (264)
- (3)
- (4)
Boiling Point
- (4)
- (1)
- (2)
- (1)
- (4)
- (1)
- (2)
- (2)
- (2)
- (5)
- (2)
- (3)
- (9)
- (2)
- (2)
- (2)
- (2)
- (2)
- (7)
- (1)
- (1)
- (2)
- (2)
- (8)
- (3)
- (2)
- (2)
- (5)
- (4)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (2)
- (2)
- (2)
- (3)
- (1)
- (1)
- (3)
- (3)
- (1)
- (2)
- (3)
- (13)
- (1)
- (2)
- (1)
- (4)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (2)
- (1)
- (1)
- (9)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (4)
- (1)
- (1)
- (1)
- (1)
- (2)
- (10)
- (1)
- (2)
- (1)
- (1)
- (3)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (3)
- (1)
- (1)
- (1)
- (1)
- (3)
- (1)
- (4)
- (2)
- (2)
- (5)
- (1)
- (2)
- (4)
- (2)
- (1)
- (2)
- (1)
- (2)
- (1)
- (2)
- (1)
- (2)
- (3)
- (3)
- (4)
- (2)
- (1)
- (3)
- (3)
- (2)
- (3)
- (1)
- (1)
- (5)
- (1)
- (3)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (4)
- (1)
- (1)
- (3)
- (1)
- (2)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (4)
- (1)
- (1)
- (1)
- (1)
- (1)
- (5)
- (1)
- (2)
- (1)
- (2)
- (2)
- (1)
- (1)
- (1)
- (3)
- (1)
- (1)
- (3)
- (6)
- (1)
- (4)
- (1)
- (2)
- (2)
- (1)
- (1)
- (2)
- (3)
- (1)
- (4)
- (3)
- (6)
- (3)
- (1)
- (9)
- (1)
- (2)
- (2)
- (2)
- (2)
- (2)
- (1)
- (1)
- (1)
- (1)
- (6)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (3)
- (3)
- (1)
- (1)
- (2)
- (1)
- (3)
- (2)
- (1)
- (2)
- (1)
- (2)
- (6)
- (2)
- (1)
- (1)
- (3)
- (9)
- (2)
- (1)
- (2)
- (1)
- (3)
- (1)
- (2)
- (1)
- (2)
- (3)
- (2)
- (6)
- (1)
- (1)
- (3)
- (1)
- (1)
- (1)
- (1)
- (3)
- (3)
- (2)
- (2)
- (1)
- (1)
- (1)
- (2)
- (3)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (3)
- (2)
- (2)
- (2)
- (2)
- (1)
- (2)
- (5)
- (1)
- (2)
- (2)
- (3)
- (1)
- (3)
- (2)
- (3)
- (9)
- (4)
- (1)
- (4)
- (4)
- (1)
- (2)
- (3)
- (4)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (7)
- (3)
- (2)
- (1)
- (2)
- (2)
- (5)
- (3)
- (1)
- (1)
- (3)
- (2)
- (1)
- (3)
- (1)
- (2)
- (3)
- (1)
- (3)
- (1)
- (1)
- (1)
- (2)
- (1)
- (4)
- (2)
- (5)
- (1)
- (3)
- (3)
- (2)
- (5)
- (2)
- (1)
- (4)
- (3)
- (3)
- (2)
- (2)
- (3)
- (3)
- (2)
- (1)
- (1)
- (2)
- (3)
- (2)
- (1)
- (1)
- (1)
- (2)
- (1)
- (2)
- (4)
- (1)
- (3)
- (3)
- (2)
- (1)
- (4)
- (1)
- (1)
- (4)
- (4)
- (1)
- (4)
- (3)
- (6)
- (2)
- (2)
- (3)
- (1)
- (1)
- (3)
- (1)
- (2)
- (1)
- (1)
- (6)
- (3)
- (1)
- (5)
- (3)
- (4)
- (2)
- (1)
- (2)
- (1)
- (2)
- (2)
- (2)
- (3)
- (1)
- (2)
- (1)
- (1)
- (2)
- (2)
- (4)
- (2)
- (1)
- (2)
- (2)
- (1)
- (2)
- (2)
- (2)
- (3)
- (4)
- (5)
- (2)
- (2)
- (2)
- (3)
- (2)
- (1)
- (3)
- (3)
- (3)
- (2)
- (2)
- (2)
- (1)
- (2)
- (6)
- (1)
- (1)
- (1)
- (2)
- (1)
- (2)
- (1)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (4)
- (1)
- (1)
- (5)
- (3)
- (5)
- (2)
- (4)
- (4)
- (2)
- (3)
- (1)
- (1)
- (1)
- (2)
- (4)
- (1)
- (1)
- (1)
- (2)
- (2)
- (1)
- (2)
- (7)
- (1)
- (3)
- (3)
- (4)
- (3)
- (3)
- (5)
- (6)
- (2)
- (2)
- (2)
- (1)
- (4)
- (2)
- (1)
- (3)
- (2)
- (1)
- (1)
- (4)
- (7)
- (1)
- (2)
- (2)
- (2)
- (2)
- (2)
- (1)
- (3)
- (3)
- (3)
- (4)
- (2)
- (3)
- (2)
- (2)
- (3)
- (2)
- (3)
- (1)
- (1)
- (2)
- (5)
- (1)
- (4)
- (2)
- (2)
- (1)
- (1)
- (3)
- (1)
- (6)
- (1)
- (1)
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Medchemexpress LLC Cridanimod | 38609-97-1 | MFCD00157050 | >=99.0% | 253.26 | 5 G
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Cridanimod | 38609-97-1 | MFCD00157050 | >=99.0% | 253.26 | 5 G
Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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6,872
Medchemexpress LLC PPM-3 | 3032388-42-1 | 98.2% | 1000.26 | 5 MG
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PPM-3 is a potent and selective PROTAC ERK5 degrader with an IC50 of 62.4 nM. It does not directly influence tumor cell growth but affects tumor development by influencing the differentiation of macrophages.
- Potent and selective PROTAC ERK5 degrader
- IC50 of 62.4 nM
- Affects tumor development by influencing macrophage differentiation
- Initiates ERK5 degradation within 2-4 hours, with peak degradation at 12 hours
- Maintains ERK5 degradation for at least 72 hours
- Shows ERK5 degradation activity in multiple cancer cell lines including H1975, HepG2, MDA-MB-231, PC-3, HCT116, and A375
Encompass Procurement Services
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Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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6,873
Medchemexpress LLC SB 415286 | 264218-23-7 | C16H10ClN3O5 | 100 MG
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SB 415286 is a potent and selective cell permeable inhibitor of GSK-3α and GSK-3β, with an IC50 of 77.5 nM and a Ki of 30.75 nM. This compound stimulates glycogen synthesis and induces transcription of a β-catenin-LEF/TCF regulated reporter gene. It is supplied as a light yellow to yellow solid.
- Potent and selective cell permeable GSK-3α and GSK-3β inhibitor.
- Stimulates glycogen synthesis in Chang human liver cell line.
- Induces transcription of a β-catenin-LEF/TCF regulated reporter gene in HEK293 cells.
- Attenuates B65 cell loss and ROS production mediated by hydrogen peroxide.
- Suppresses immunoprecipitated GSK3 activity by 97% at 50 μM.
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6,874
Medchemexpress LLC Transketolase-IN-2 | 2757552-21-7 | C18H9F3N2O3S | 50 MG
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Transketolase-IN-2 (compound 4w) is a potent Transketolase inhibitor. It demonstrates strong inhibition of *Digitaria sanguinalis* and *Amaranthus retroflexus* (over 90% at 200 mg/L and approximately 80% at 100 mg/L). It can be used in studies of weed control.
- Potent transketolase inhibitor
- Strong inhibitory effects against *Digitaria sanguinalis* (92% root inhibition, 90% stem inhibition at 200 mg/L)
- Strong inhibitory effects against *Amaranthus retroflexus* (91% root inhibition, 90% stem inhibition at 200 mg/L)
- Useful in studies of weed control
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6,875
LIFE TECHNOLOGIES
QGP106 MULTIPLEX 6PLEX 1PLATE
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6,876
Medchemexpress LLC Gsk737 | 2748687-95-6 | C20H21N5O2 | 50 MG
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GSK737 is an inhibitor of BD1 and BD2. It demonstrates low clearance and good solubility and permeability in rat models.
- Functions as a BD1 and BD2 inhibitor.
- Exhibits low clearance in rat.
- Possesses good solubility in rat.
- Demonstrates good permeability in rat.
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6,877
Medchemexpress LLC MEL24 | 642072-48-8 | C17H18N4O3 | 1 ML
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MEL24 is an Mdm2 E3 ligase inhibitor that reduces cell survival and increases sensitivity to DNA damaging agents in a p53-dependent manner for in vitro antitumor studies. It is for research use only.
- Mdm2 E3 ligase inhibitor
- Reduces cell survival
- Increases sensitivity to DNA damaging agents
- P53-dependent action
- For in vitro antitumor studies
- Acts on 293T cells with ED50 value of 9.2 μM
- Activates p53 in HCT116 cells
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6,878
LIFE TECHNOLOGIES
QGP316 MULTIPLEX 16PLEX 10PLATE
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6,879
Medchemexpress LLC PF 05089771 | 1235403-62-9 | 99.9% | 100 MG
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PF 05089771 is a potent, orally active, and selective arylsulfonamide Nav1.7 inhibitor. It is currently being studied for its potential use in pain management and diabetic neuropathy.
- Potent, orally active, and selective arylsulfonamide Nav1.7 inhibitor
- IC50 values of 11 nM for hNav1.7, 12 nM for cynNav1.7, 13 nM for dogNav1.7, 171 nM for ratNav1.7, and 8 nM for musNav1.7
- More than 1000-fold selective over tetrodotoxin-resistant (TTX-R) Nav1.5 and Nav1.8 channels (IC50s >10 μM)
- Exhibits a range of selectivity over TTX-sensitive (TTX-S) channels (10-fold for Nav1.2 to 900-fold for Nav1.3 and Nav1.4)
- Blocks the majority of TTX-S current (75.5 ± 10.5%) at 30 nM, with complete block at 100 nM
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6,880
Medchemexpress LLC LI-2242 | 2762762-17-2 | C20H18Cl2N2O3 | 50 MG
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LI-2242 is an inositol hexakisphosphate kinase (IP6K) inhibitor, demonstrating potent inhibition of IP6K1, IP6K2, IP6K3, and IPMK. It is suitable for research in areas such as type II diabetes, obesity, metabolic complications, venous thrombosis, and psychiatric disorders.
- Inhibits IP6K1 with an IC50 of 31 nM
- Inhibits IP6K2 with an IC50 of 42 nM
- Inhibits IP6K3 with an IC50 of 8.7 nM
- Inhibits IPMK with an IC50 of 1944 nM
- Useful for research on type II diabetes, obesity, and metabolic complications
- Applicable for studies on venous thrombosis and psychiatric disorders
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6,881
Medchemexpress LLC PTP inhibitor 1 | 2632-13-5 | 99.6% | 229.07 | 1 ML
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PTP inhibitor 1 is a protein tyrosine phosphatase (PTP) inhibitor, with anti-angiogenic effect. It shows anti-angiogenic activity with an IC50 of 3.7 μM for HUVECs.
- Protein tyrosine phosphatase (PTP) inhibitor
- Anti-angiogenic effect
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6,882
Medchemexpress LLC Ezatiostat | 168682-53-9 | 99.7% | 529.65 | 50 MG
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Ezatiostat is a tripeptide analog of glutathione that acts as a selective, orally active glutathione S-transferase P1-1 (GSTP1) inhibitor. It activates JNK by inhibiting GSTP1 and has shown potential for treating myelodysplastic syndrome (MDS). This compound stimulates both lymphocyte production and bone marrow progenitor proliferation.
- Activates JNK by inhibiting GSTP1
- Stimulates lymphocyte production
- Stimulates bone marrow progenitor proliferation
- Potential for treating myelodysplastic syndrome (MDS)
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6,883
Medchemexpress LLC SJPYT-195 | 2973762-16-0 | C35H34N6O8 | 25 MG
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SJPYT-195 is a cytotoxic GSPT1 degrader that can be utilized for PROTAC synthesis. It effectively reduces endogenous PXR protein in colorectal SNU-C4 cell lines by degrading GSPT1. This compound is supplied as a white to off-white solid, with a purity of 98.07%, and is intended for research use only.
- Cytotoxic GSPT1 degrader
- Utilized for PROTAC synthesis
- Potently reduces endogenous PXR protein
- Mechanism involves GSPT1 degradation
- Supplied as a white to off-white solid
- High purity (98.07%)
- For research use only
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6,884
Medchemexpress LLC Empagliflozin (Standard) | 864070-44-0 | C23H27ClO7 | 5 MG
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Empagliflozin (Standard) is an analytical standard of Empagliflozin, intended for research and analytical applications. It functions as a selective sodium glucose cotransporter-2 (SGLT-2) inhibitor with an IC50 of 3.1 nM for human SGLT-2. This compound is used as a reference standard in assays.
- Analytical standard for research and analytical applications
- Selective sodium glucose cotransporter-2 (SGLT-2) inhibitor
- Commonly utilized in qualitative, quantitative and methodological research experiments in HPLC, GC and MS
- Features an IC50 of 3.1 nM for human SGLT-2
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6,885
![eMolecules 10022-66-9 | POTASSIUM DIOXIDODIOXOOSMIUM DIHYDRATE | AstaTech | MFCD00149919 | 370.470 | H6K2O6Os | 95.000 | O.O.[OH-].[OH-].[O--].[O--].[K+].[K+].[Os+4] | 1g | 444382694](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000170882.jpg-250.jpg)
eMolecules 10022-66-9 | POTASSIUM DIOXIDODIOXOOSMIUM DIHYDRATE | AstaTech | MFCD00149919 | 370.470 | H6K2O6Os | 95.000 | O.O.[OH-].[OH-].[O--].[O--].[K+].[K+].[Os+4] | 1g | 444382694
POTASSIUM DIOXIDODIOXOOSMIUM DIHYDRATE | AstaTech | 10022-66-9 | MFCD00149919 | 370.470 | H6K2O6Os | 95.000 | O.O.[OH-].[OH-].[O--].[O--].[K+].[K+].[Os+4] | 1g | 444382694
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